OVOTRANSFERRIN enhances milk antibacterial properties and makes it comparable to human milk

OVOTRANSFERRIN promotes Heat Shock Proteins (HSP) production against skin damages and stress

OVOTRANSFERRIN induce HSPs production in the skin providing protection against cold stress and other environmental factors

OVOTRANSFERRIN

OVOTRANSFERRIN, also called conalbumin, is a glycoprotein with a molecular weight of 76,000OVOTRANSFERRIN comprises approximately 13% of the protein content of egg albumen. More than sixty years ago, researchers determined that OVOTRANSFERRIN is an iron-binding protein, making the iron in a bacterial culture medium nutritionally unavailable to potentially harmful micro-organisms, such as Schigella dysenteria (for which iron is an essential nutrient).

These same investigators later determined that a fraction of human blood serum exerts the same iron-binding action as OVOTRANSFERRIN. This blood serum protein was initially named siderophilin, but today is known as human transferrin. OVOTRANSFERRIN and blood transferrin are now known to have similar amino acid compositions (see table), as well as similar carbohydrate content.

 Table: Comparison of Amino Acids Profiles
Amino Acids Ovotransferrin Human Transferrin Bovine Serum Transferrin
Lysine 53 51 52
Histidine 13 19 15
Arginine 33 24 24
Aspartic Acid 77 81 74
Threonine 38 30 44
Serine 46 40 49
Glutamic Acid 62 58 63
Proline 33 30 35
Glycine 58 54 45
Alanine 38 59 49
Half Cystine 12 35 34
Valine 54 43 44
Methionine 10 4 7
Isoleucine 29 14 17
Leucine 51 47 45
Tyrosine 19 24 20
Phenylalanine 27 28 25
Tryptophan 11 9 10

faviconAdvantages & benefits

As one of the largest manufacturers and suppliers worldwide of egg white proteins, Neova Technologies Inc.’s advanced extraction and purification processes yield products that are consistently chosen over other competitive products. All extraction and refining is done under cGMP guidelines for active pharmaceutical ingredients (API).

A key benefit associated with using Neova Technologies Inc.’s OVOTRANSFERRIN lies in the full range of services, including both technical and applications support that Neova provides. Neova Technologies works with its customers to meet their unique product specifications.

An important advantage to using Neova Technologies Inc.’s OVOTRANSFERRINis the elimination of the risk of disease associated with bovine and human derived transferrins.

faviconApplications

Transferrins have been identified as a required media ingredient for the maturation of cells. The role of transferrins in culture systems is to provide iron to cells and to detoxify the media by binding contaminating metal ions, such as zinc, iron, and aluminum in their di and trivalent forms.

OVOTRANSFERRIN belongs to a group of proteins called metalloproteinases that have been found to induce the production of heat shock proteins (HSPs). Clinical trials with OVOTRANSFERRIN have found that it is able to induce HSPs in the skin, which provide protection against cold stress and other environmental factors.

HSPs play a fundamental role in life-essential processes and are associated with many areas of biology and medicine. They are known to help cells disassemble and dispose of damaged proteins and to help in the making and transport of new proteins. The role of HSPs in the aging process is not yet clear. However, the ability of OVOTRANSFERRIN to induce HSP production suggests it can be effectively utilized in personal care skin creams and moisturizers.

OVOTRANSFERRIN, like serum transferrin, is also similar in structure and function to lactoferrin from milk. However, OVOTRANSFERRIN can be extracted in larger quantities and is suitable for use in therapeutic programs.

Addition of OVOTRANSFERRIN to cow’s milk (which is generally low in transferrins) enhances its antibacterial property and makes it comparable to human milk.

Non Warranty: The information contained herein is provided in good faith and, to the best of our knowledge, is true and correct. However, no warranty or guarantee is implied or inferred and the information may be subject to change without further notice. Neova Technologies Inc.’s products are sold with the understanding that the purchaser will conduct tests to determine the suitability of these products for their particular use.